CD73 Monoclonal Antibody (A6G1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550565-Each-of-1 | In Stock | ₹ 41,741.00 |
FEMA550565 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,741.00
GST (18%): ₹ 7,513.38
Total Price: ₹ 49,254.38
Antigen
CD73
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P21589
Gene Symbols
NT5E
Immunogen
Recombinant protein within Human CD73 aa 27-549/574.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
A6G1
Conjugate
Unconjugated
Gene
NT5E
Gene Alias
2210401F01Rik, 5 nucleotidase, ecto, 5' nucleotidase, ecto, 5'-NT, 5'-nucleotidase, 5'-nucleotidase ecto, 5'-nucleotidase, ecto (CD73), AI447961, CALJA, CD73, E5NT, ecto-5'-nucleotidase, eN, eNT, NT, Nt5, Nt5e, NTE, Purine 5-Prime-Nucleotidase
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
4907
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Positive control: U87MG cell lysates, NCI-H441 xenograft tissue, U87MG xenograft tissue, U87-MG
- Predicted band size: 63 kDa Subcellular Location: Cell membrane
- CD73 (Ecto-5-prime-nucleotidase, 5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP
- CD73 consists of a dimer of 2 identical 70 kDa subunits bound externally to the plasma membrane by a glycosyl phosphatidyl inositol linkage
- CD73 is used as a marker of lymphocyte differentiation
- Consequently, a deficiency of CD73 occurs in a variety of immunodeficiency diseases
- Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from CD73 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate
- The CD73 gene has been localized to 6q14-q21 by immunofluorescence and a study of a panel of human x mouse hybrids that contained fragments of chromosome 6 as translocations
- Defects in the CD73 gene can lead to the calcification of joints and arteries, and intestinal tuberculosis
- Two transcript variants encoding different isoforms of CD73 have been found.