AOX1 Recombinant Rabbit Monoclonal Antibody (PSH0-17), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550783-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550783 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
AOX1
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O54754, Q06278, Q9Z0U5
Gene Symbols
AOX1
Immunogen
Synthetic peptide within human AOX1 aa 1301-1338/1338.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone
PSH0-17
Conjugate
Unconjugated
Gene
AOX1
Gene Alias
AI196512, AI255253, Aldehyde oxidase, aldehyde oxidase (female form), aldehyde oxidase 1, aldehyde oxidase 2, Ao, AOH1, Aox1, Aox-1, Aox2, Aox-2, Azaheterocycle hydroxylase, azaheterocycle hydroxylase 1, Moro, Retinal oxidase, Ro
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11761, 316, 54349
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Rat liver tissue lysates, rat liver tissue, rat adrenal gland tissue, human kidney tissue, mouse testis tissue, Hela
- Predicted band size: 148 kDa Subcellular Location: Cytoplasm
- AOX1 (Aldehyde oxidase 1) is a 1338 amino acid cytoplasmic protein that catalyzes the oxidation of a variety of aldehydes, leading to the production of hydrogen peroxide
- Under certain conditions, AOX1 can catalyze the formation of the superoxide free radical
- Defects in oxygen radical metabolism have been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS), an autosomal dominant neurodegenerative disorder characterized by the death of motor neurons in the spinal cord, brain and brainstem
- Significantly, AOX1 is highly expressed in the ventral horn of the spinal cord and the gene that encodes AOX1 is located in a chromosomal region that is frequently found to be implicated in ALS2
- This evidence suggests that AOX1 is a candidate gene for ALS2.