Placental Alkaline Phosphatase Recombinant Rabbit Monoclonal Antibody (PD00-19), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550692-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550692 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
Placental Alkaline Phosphatase
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P05187
Gene Symbols
ALPP
Immunogen
Recombinant fragment within Human Placental alkaline phosphatase (PLAP) aa 150-300/535.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
PD00-19
Conjugate
Unconjugated
Gene
ALPP
Gene Alias
Alkaline phosphatase placental type, Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, Alp1, ALPP, AP-TNAP, DOA1, FLJ11281, FLJ40094, FLJ61142, FLJ93059, Germ-cell alkaline phosphatase, glycerophosphatase, HOPS, MGC161443, MGC167935, nagao Isozyme, P PLAP, PALP, PLA2P, PLAA, placental alkaline phosphatase 1, placental heat-stable alkaline phosphatase, PLAP, PLAP1, PLAP-1, rCG23846-like, Regan isozyme, TNAP, TNSALP
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
250
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Human placenta tissue lysates, human placenta tissue, human seminoma tissue
- Predicted band size: 58 kDa Subcellular Location: Cell membrane
- Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes
- There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized
- Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation
- Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors
- Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA)
- A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development
- Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects
- The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.