FEMA550707
Thyroid Peroxidase Recombinant Rabbit Monoclonal Antibody (JE60-40), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550707-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550707 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
Thyroid Peroxidase
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
P07202
Gene Symbols
TPO
Immunogen
Recombinant protein within Human Thyroid Peroxidase/TPO aa 834-933/933.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Clone
JE60-40
Conjugate
Unconjugated
Gene
TPO
Gene Alias
EC 1.11.1, LOW QUALITY PROTEIN: thyroid peroxidase, MSA, TDH2A, thyroid microsomal antigen, thyroid peroxidase, thyroid peroxidase (332 AA), thyroperoxidase, TPO, TPX, TPXEC 1.11.1.8
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7173
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: Human thyroid tissue, human thyroid carcinoma tissue
- Predicted band size: 103 kDa Subcellular Location: Membrane
- Thyroid Peroxidase is a gene that encodes for a membrane-bound glycoprotein, which functions as an enzyme and plays a crucial role in the proper functioning of the thyroid gland
- This protein is responsible for the iodination of tyrosine residues in thyroglobulin and the formation of phenoxy-ester between pairs of iodinated tyrosines, which leads to the production of thyroid hormones such as thyroxine and triiodothyronine
- Mutations in this gene are known to cause several disorders related to thyroid hormone production, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA
- Several transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants remains undetermined
- Diseases associated with TPO include Thyroid Dyshormonogenesis 2A and Congenital Hypothyroidism.