FEMA550740

RALA Recombinant Rabbit Monoclonal Antibody (JE54-12), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550740-Each-of-1 In Stock ₹ 42,275.00

FEMA550740 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

RALA

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

P11233

Gene Symbols

Rala

Immunogen

Recombinant protein within Human RALA aa 107-206/206.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone

JE54-12

Conjugate

Unconjugated

Gene

Rala

Gene Alias

3010001O15Rik, AW322615, MGC48949, Ral, -ral simian leukemia viral oncogene homolog A (ras related), RALA, Ral-a, ral-A protein, RALA Ras like proto-oncogene A, Ras family small GTP binding protein RALA, ras related GTP binding protein A, Rasl1, RAS-like protein A, RAS-like, family 1, ras-related protein Ral-A, v-ral simian leukemia viral oncogene homolog A (ras related)

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5898

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: LOVO cell lysate, HCT116 cell lysate, HT-29 cell lysate, SW480 cell lysate, 293 cell lysate, human kidney tissue lysate, human colon tissue, human colon carcinoma tissue, human kidney tissue, HUVEC
  • Predicted band size: 24 kDa Subcellular Location: Cell membrane, Mitochondrion
  • Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking
  • Accomplishes its multiple functions by interacting with distinct downstream effectors
  • Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles
  • Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow
  • The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling
  • Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor
  • Required for anchorage-independent proliferation of transformed cells.