TRF2 Recombinant Rabbit Monoclonal Antibody (JE37-57), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550791-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550791 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
TRF2
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q15554
Gene Symbols
TERF2
Immunogen
Recombinant protein within Human TRF2 aa 1-100/542.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
JE37-57
Conjugate
Unconjugated
Gene
TERF2
Gene Alias
Telomeric DNA-binding protein, telomeric repeat binding factor 2, telomeric repeat binding protein 2, telomeric repeat-binding factor 2, TERF2, TRBF2, TRF2, TTAGGG repeat-binding factor 2
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
7014
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: SiHa cell lysate, Jurkat cell lysate, human colon carcinoma tissue, human testis tissue, SiHa
- Predicted band size: 60 kDa Subcellular Location: Nucleus, Chromosome, telomere
- TRF2 is a ubiquitously expressed protein that is implicated in the control of telomere length
- TRF2, like TRF1 contains a Myb-related DNA binding motif
- It binds to duplex TTAGGG repeats and is localized to all human telomeres in metaphase chromosomes
- TRF2 is thought to protect chromosome ends by maintaining the correct structure at telomere termini
- The use of mutant forms of TRF2 has implicated a role for TRF2 in the prevention of senescence in primary human cells
- Recently, it has been shown that inhibition of TRF2 resulted in apoptosis in a subset of mammalian cell types.