FEMA550821

PRMT6 Recombinant Rabbit Monoclonal Antibody (JE36-57), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550821-Each-of-1 In Stock ₹ 42,275.00

FEMA550821 - Each of 1

₹ 42,275.00

In Stock

Quantity

1

Base Price: ₹ 42,275.00

GST (18%): ₹ 7,609.50

Total Price: ₹ 49,884.50

Antigen

PRMT6

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q6NZB1, Q96LA8

Gene Symbols

PRMT6

Immunogen

Synthetic peptide within Human PRMT6 aa 191-240/375.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

Applications

Western Blot

Clone

JE36-57

Conjugate

Unconjugated

Gene

PRMT6

Gene Alias

AW124876, BB233495, FLJ10559, FLJ51477, heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6, Histone-arginine N-methyltransferase PRMT6, HMT1 hnRNP methyltransferase-like 6, Hrmt1l6, PRMT6, PRMT-6, protein arginine methyltransferase 6, protein arginine N-methyltransferase 6

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

295384, 55170, 99890

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

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Description

  • Positive control: Human kidney tissue lysate, mouse kidney tissue lysate, mouse testis tissue lysate, rat kidney tissue lysate, rat testis tissue lysate, 293T cell lysate, HEK-293 cell lysate
  • Predicted band size: 42 kDa Subcellular Location: Nucleus
  • Protein arginine N-methyltransferase 6 (PRMT6) PRMT6 demonstrates type I PRMT activity, capable of forming both omega-N monomethylarginine and asymmetric dimethylarginine derivatives on the recombinant glycine- and arginine-rich substrates
  • cts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1
  • Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator
  • May play a role in innate immunity against HIV-1 in case of infection by methylating and impairing the function of various HIV-1 proteins such as Tat, Rev and Nucleocapsid protein p7.