ATG4B Recombinant Rabbit Monoclonal Antibody (JE59-97), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550822-Each-of-1 | In Stock | ₹ 42,275.00 |
FEMA550822 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,275.00
GST (18%): ₹ 7,609.50
Total Price: ₹ 49,884.50
Antigen
ATG4B
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
Q8BGE6, Q9Y4P1
Gene Symbols
Atg4b
Immunogen
Recombinant protein within Human ATG4B aa 221-320/393.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Western Blot
Clone
JE59-97
Conjugate
Unconjugated
Gene
Atg4b
Gene Alias
2510009N07Rik, APG4 (ATG4) autophagy-related homolog B, APG4 autophagy 4 homolog B, APG4B, ATG4 autophagy related 4 homolog B, Atg4b, atg4b protein, Atg4bl, AUT2B, Aut2B1, Aut2b2, AUTL1, AUT-like 1 cysteine, AUT-like 1 cysteine endopeptidase, AUT-like 1, cysteine endopeptidase, autophagin 1, autophagin-1, Autophagin-2B, autophagy related 4 homolog B, autophagy related 4B cysteine peptidase, autophagy related 4B, cysteine peptidase, autophagy-related 4B, autophagy-related cysteine endopeptidase 1, Autophagy-related cysteine endopeptidase 2B, autophagy-related protein 4 homolog B, AW048066, bAut2B, Cysteine protease ATG4B, cysteine protease involved in autophagy APG4-B, hAPG4B, KIAA0943
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
23192, 316640, 66615
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Positive control: 293T cell lysate, Jurkat cell lysate, PC-12 cell lysate, mouse heart tissue lysate, mouse pancreas tissue lysate
- Predicted band size: 44 kDa Subcellular Location: Cytoplasm, cytosol, Cytoplasmic vesicle, autophagosome, Endoplasmic reticulum, Mitochondrion
- Cysteine protease ATG4b is an enzyme which is coded by ATG4b gene
- Autophagy is a critical cellular homeostatic process that controls the turnover of damaged organelles and protein
- ATG4b is a deubiquitin-like protease that plays dual roles in the core machinery of autophagy
- ATG4b, cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine
- Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy
- ATG4b is mainly expressed in the skeletal muscle, brain, heart, liver and pancreas.