Arginase 1 Monoclonal Antibody (C7), Invitrogen™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550871-Each-of-1 | In Stock | ₹ 36,312.00 |
FEMA550871 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,312.00
GST (18%): ₹ 6,536.16
Total Price: ₹ 42,848.16
Antigen
Arginase 1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4
Gene Accession No.
P05089, Q95JC8
Gene Symbols
ARG1
Immunogen
Recombinant Human ARG protein, Met1-Lys322 (Accession #P05089)
Quantity
200 μL
Primary or Secondary
Primary
Target Species
Human, Porcine
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
C7
Conjugate
Unconjugated
Gene
ARG1
Gene Alias
AI, A-I, AI type I arginase, AI256583, Arg1, Arg-1, Arginase, arginase 1, arginase 1 liver, arginase 1, liver, arginase I, arginase, liver, Arginase1, arginase-1, HGNC:663, Liver Arginase, Liver-type arginase, PGIF, similar to arginase, type I, Type 1 Arginase, type I arginase
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
383, 397115
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1 κ
Related Products
Description
- Arginase-1 (Arg1) is a 35 kDa enzyme converting L-arginine to urea and L-ornithine, which is the final step in the urea cycle
- The resulting polyamines are important for cell proliferation and removal of toxins that arise from protein degradation
- By degrading arginine, Arginase 1 deprives NO synthase of its substrate and down-regulates nitric oxide production
- In both human and mouse, Arginase 1 is expressed in the liver, neutrophils, myeloid derived suppressor cells (MDSC) and neural stem cells
- In human, expression in blood neutrophils but not in CCR3+ granulocytes has been reported
- In mice, expression of Arginase 1 is one of the hallmarks of alternatively activated macrophages (M2a)
- Arginase-1 may be expressed in the myeloid cells infiltrating tumors, and is typically found in the majority of hepatocellular carcinomas
- Defects in Arginase 1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia.