Complement C4b Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEPA5144127-Each-of-1 | In Stock | ₹ 31,773.00 |
FEPA5144127 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 31,773.00
GST (18%): ₹ 5,719.14
Total Price: ₹ 37,492.14
Antigen
Complement C4b
Classification
Polyclonal
Conjugate
Unconjugated
Gene
C4B
Gene Alias
Acidic complement C4, Basic complement C4, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3, c4 complement, C4A, C4a anaphylatoxin, C4A13, C4A91, C4B, C4B_2, C4B1, C4B12, C4B2, C4B3, C4B5, C4b-A, C4b-B, C4BD, C4d-A, C4d-B, C4F, CH, Chido form of C4, CO4, Complement C4 beta chain, Complement C4 gamma chain, Complement C4-A, Complement C4-A alpha chain, Complement C4-B, Complement C4-B alpha chain, complement C4B1a, complement C4-B-like, complement component 4B (Chido blood group), complement component 4B (Chido blood group), copy 2, CPAMD2, CPAMD3, DADB-112B14.11, FLJ60561, MGC164979
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100293534, 721
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Applications
ELISA, Immunohistochemistry (Paraffin)
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene Accession No.
P0C0L5
Gene Symbols
C4B, C4B_2
Immunogen
Recombinant Human Complement C4-B protein (1454-1744AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- This gene encodes the basic form of complement factor 4, part of the classical activation pathway
- The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion
- The trimer provides a surface for interaction between the antigen-antibody complex and other complement components
- The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation
- Deficiency of this protein is associated with systemic lupus erythematosus
- This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6
- Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene
- In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9.