FEPA5143803

Complement C4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5143803-Each-of-1 In Stock ₹ 55,002.00

FEPA5143803 - Each of 1

₹ 55,002.00

In Stock

Quantity

1

Base Price: ₹ 55,002.00

GST (18%): ₹ 9,900.36

Total Price: ₹ 64,902.36

Antigen

Complement C4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

C4A

Gene Alias

acidic C4; acidic complement C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4; c4 complement; C4-1; C4a; C4a anaphylatoxin; C4A2; C4A3; C4A4; C4A6; C4AD; C4B; C4B_2; C4B1; C4B12; C4B2; C4B3; C4B5; C4b-A; C4b-B; C4BD; C4d-A; C4d-B; C4F; C4S; CH; Chido form of C4; CO4; Complement C4; Complement C4 alpha chain; Complement C4 beta chain; Complement C4 gamma chain; Complement C4-A; Complement C4-A alpha chain; Complement C4-B; Complement C4-B alpha chain; complement C4B1a; complement component 4 (within H-2S); complement component 4, gene 1; complement component 4A (Rodgers blood group); complement component 4B (Chido blood group); complement component 4B (Childo blood group); CPAMD2; CPAMD3; DADB-112B14.11; DAMC-258G8.6; FLJ60561; MGC164979; MHC class III region complement; RG; Rodgers form of C4; sex-limited protein; Slp; Ss

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

24233, 406161

Content And Storage

4° C

Isotype

Ig

Applications

Immunoprecipitation, Inhibition Assays

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

P08649

Gene Symbols

C4A, C4B

Immunogen

The polyclonal antibody reacts with Rat C4

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Rat

Form

Liquid

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Description

  • This gene encodes the acidic form of complement factor 4, part of the classical activation pathway
  • The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion
  • The trimer provides a surface for interaction between the antigen-antibody complex and other complement components
  • The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation
  • Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus
  • This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6
  • Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene.