FEPA5144196

IRAK4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEPA5144196-Each-of-1 In Stock ₹ 31,773.00

FEPA5144196 - Each of 1

₹ 31,773.00

In Stock

Quantity

1

Base Price: ₹ 31,773.00

GST (18%): ₹ 5,719.14

Total Price: ₹ 37,492.14

Antigen

IRAK4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRAK4

Gene Alias

8430405M07Rik, 9330209D03Rik, interleukin 1 receptor associated kinase 4, interleukin-1, interleukin-1 receptor-associated kinase 4, IPD1, Irak4, IRAK-4, NY-REN-64, REN64, renal carcinoma antigen NY-REN-64

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

51135

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

Applications

ELISA, Immunoprecipitation, Western Blot

Concentration

0.36 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9NWZ3

Gene Symbols

IRAK4

Immunogen

Recombinant Human Interleukin-1 receptor-associated kinase 4 protein (1-220AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
  • Overexpression of IRAK-4 activates NF-kappa-B and MAPK pathways
  • IRAK-4 interacts with and phosphorylates IRAK-1
  • IRAK-4-deficient animals are completely resistant to the challenge with LPS
  • Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges
  • Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity.