PIPA551424
Emerin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA551424-Each-of-1 | In Stock | ₹ 52,599.00 |
PIPA551424 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,599.00
GST (18%): ₹ 9,467.82
Total Price: ₹ 62,066.82
Antigen
Emerin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Emd
Gene Alias
AW550900; EDMD; EMD; Emerin; LEM domain containing 5; LEMD5; STA
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13726, 2010, 25437
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.2 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
O08579, P50402, Q63190
Gene Symbols
Emd
Immunogen
Recombinant protein corresponding to Human Emerin
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: ASSYSFSDLN STRGDADMYD LPKKEDALLY QSKGYNDDYY EESYFTTRTY GEPESAGPSR AVRQSVTSFP DADAFHHQVH DDDLLSSSEE ECKDRERPMY GRDSACQSIT HY Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 73%
- Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight
- The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is an enzyme essential for DNA repair of the major kinds of solar μgtraviolet (UV)-induced DNA damages
- Human XPG nuclease makes the 3' incision during nucleotide excision repair of DNA
- The enzyme cleaves model DNA bubble structures specifically near the junction of unpaired DNA with a duplex region
- A 29-amino acid region of human XPG (residues 981-1009) contains the PCNA binding activity
- A conserved arginine in XPG (Arg992) is crucial for its PCNA binding activity
- Replication Protein A (RPA) binds specifically and directly to two excision repair proteins, the xeroderma pigmentosum damage-recognition protein XPA and the endonuclease XPG.