ABCA1 Monoclonal Antibody (6B7A11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548356-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548356 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
ABCA1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
O95477
Gene Symbols
Abca1
Immunogen
Purified recombinant fragment of human ABCA1 (AA: 2081-2261) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
6B7A11
Conjugate
Unconjugated
Gene
Abca1
Gene Alias
ABC 1; ABC 1 antibody; ABC Transporter 1; Abc1; ABC-1; ABC1 antibody; Abca1; ATP binding cassette subfamily A member 1; ATP-binding cassette 1; ATP-binding cassette sub-family A member 1; ATP-binding cassette transporter 1; ATP-binding cassette transporter A1; ATP-binding cassette, subfamily A (ABC1), member 1; ATP-binding cassette, sub-family A (ABC1), member 1; ATP-binding cassette, sub-family A member 1; CERP; CERP antibody; Cholesterol efflux regulatory protein; HDLDT1; membrane-bound; phospholipid-transporting ATPase ABCA1; phospholipid-transporting ATPase ABCA1; ATP-binding cassette sub-family A member 1; TGD
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
19
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG2a
Related Products
Description
- Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD)
- TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking
- ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell
- It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux
- Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.