FERMA548385

BAK Monoclonal Antibody (2H9H7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548385-Each-of-1 In Stock ₹ 43,565.50

FERMA548385 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

BAK

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q16611

Gene Symbols

BAK1

Immunogen

Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

2H9H7

Conjugate

Unconjugated

Gene

BAK1

Gene Alias

Apoptosis regulator BAK; BAK; Bak1; BAK-LIKE; BCL2 antagonist/killer 1; Bcl2 homologous antagonist/killer; Bcl-2 homologous antagonist/killer; BCL2-antagonist/killer 1; BCL2L7; bcl2-L-7; BCL2-like 7 protein; BCL2-like 7protein; bcl-2-like protein 7; Bcl-2-likeous antagonist/killer; CDN1; MGC117255; MGC3887; N-Bak; N-BAK1; pro-apoptotic protein BAK

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

578

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2b

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Description

  • The protein encoded by this gene belongs to the BCL2 protein family
  • BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities
  • This protein localizes to mitochondria, and functions to induce apoptosis
  • It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c
  • This protein also interacts with the tumor suppressor P53 after exposure to cell stress.