FERMA548780

PINK1 Monoclonal Antibody (3A9F8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548780-Each-of-1 In Stock ₹ 43,565.50

FERMA548780 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

PINK1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

Q9BXM7

Gene Symbols

PINK1

Immunogen

Purified recombinant fragment of human PINK1 (AA: 112-273) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

3A9F8

Conjugate

Unconjugated

Gene

PINK1

Gene Alias

1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

65018

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

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Description

  • PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes
  • The kinase domain of PINK1 appears to be critical in its protective effects
  • Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress
  • Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes
  • When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson's disease are triggered.