FERMA548652

CD170 (Siglec F) Monoclonal Antibody (3F5A3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA548652-Each-of-1 In Stock ₹ 43,565.50

FERMA548652 - Each of 1

₹ 43,565.50

In Stock

Quantity

1

Base Price: ₹ 43,565.50

GST (18%): ₹ 7,841.79

Total Price: ₹ 51,407.29

Antigen

CD170 (Siglec F)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

O15389

Gene Symbols

SIGLEC5

Immunogen

Purified recombinant fragment of human CD170 (AA: extra 17-230) expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Western Blot

Clone

3F5A3

Conjugate

Unconjugated

Gene

SIGLEC5

Gene Alias

CD170; CD33 antigen-like 2; CD33L2; mSiglec-F; OB-binding protein 2; OBBP2; OB-BP2; Obesity-binding protein 2; sialic acid binding Ig like lectin 5; sialic acid binding Ig-like lectin 5; sialic acid binding Ig-like lectin F; sialic acid-binding Ig-like lectin 5; Sialic acid-binding Ig-like lectin F; sialic acid-binding immunoglobulin-like lectin 5; sialic acid-binding lectin Siglec-F; Siglec; SIGLEC5; siglec-5; Siglecf; Siglec-F

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

8778

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG2a

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Description

  • SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells
  • This protein binds equally to alpha2,3-linked and alpha2,6-linked sialic acid
  • The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface
  • This molecule is expressed by monocytic/myeloid lineage cells
  • SIGLEC5 is found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus
  • It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation.