ATG16L1 Monoclonal Antibody (8F8C2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA548758-Each-of-1 | In Stock | ₹ 43,565.50 |
FERMA548758 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,565.50
GST (18%): ₹ 7,841.79
Total Price: ₹ 51,407.29
Antigen
ATG16L1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
Q676U5
Gene Symbols
ATG16L1
Immunogen
Purified recombinant fragment of human ATG16L1 (AA: 11-257) expressed in E. Coli.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
Clone
8F8C2
Conjugate
Unconjugated
Gene
ATG16L1
Gene Alias
1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; atg16; ATG16 autophagy related 16-like 1; ATG16A; Atg16l; Atg16l1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
55054
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG1
Related Products
Description
- Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans
- It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10)
- ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerisation with ATG16L to form an 800 kDa complex called the Atg16L complex
- This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy
- However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.