CD55 Monoclonal Antibody (1C6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549015-Each-of-1 | In Stock | ₹ 56,248.00 |
FERMA549015 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,248.00
GST (18%): ₹ 10,124.64
Total Price: ₹ 66,372.64
Antigen
CD55
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Accession No.
P08174
Gene Symbols
CD55
Immunogen
Purified DAF from pooled human erythrocyte stroma.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone
1C6
Conjugate
Unconjugated
Gene
CD55
Gene Alias
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
1604
Content And Storage
4° C
Isotype
IgG1
Related Products
Description
- CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade
- Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97
- In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis
- CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail
- In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans
- CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways
- CD55 carries the Cromer related blood group antigens
- Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels
- CD55 has been studied to have a role in prostate cancer growth and survival.