CD55 Monoclonal Antibody (RDII-24), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549017-Each-of-1 | In Stock | ₹ 56,248.00 |
FERMA549017 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,248.00
GST (18%): ₹ 10,124.64
Total Price: ₹ 66,372.64
Antigen
CD55
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and no preservative
Gene Alias
CD55; CD55 antigen; CD55 molecule (Cromer blood group); CD55 molecule, decay accelerating factor for complement; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay-accelerating factor; complement decay-accelerating factor, GPI-anchored; complement-glycosylphosphatidylinositol; CR; CROM; Cromer blood group; Daf; Daf1; DAF-GPI; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form; GPI anchor addition signal; GPI-DAF; RP11-357P18.1; TC
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
64036
Content And Storage
4° C
Isotype
IgG1
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot
Clone
RDII-24
Conjugate
Unconjugated
Gene
CD55
Gene Symbols
CD55
Immunogen
NIH-3T3 cells expressing GPI-anchored rat DAF
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Rat
Form
Liquid
Related Products
Description
- CD55 (decay-accelerating factor, DAF) is a GPI-anchored membrane glycoprotein that protects autologous cells from classical and alternative pathway of complement cascade
- Bidirectional interactions between CD55 and CD97 are involved in T cell regulation and CD55 can regulate complement when bound to CD97
- In tumors, CD55 promotes neoangiogenesis, tumorigenesis, invasiveness and evasion of apoptosis
- CD55 is a 70 kDa glycoprotein (in erythrocytes) anchored in the membrane by glycosylphosphatidylinositol tail
- In other cells, the apparent molecular weight is somewhat larger for CD55 and has a substantial content of O-glycans
- CD55 binds to activated C4b or C3b complement fragments on the cell surface, preventing the assembly and accelerating the decay of both classical and alternative pathways
- CD55 carries the Cromer related blood group antigens
- Two alternatively spliced transcripts encoding CD55 have been identified, and the predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels
- CD55 has been studied to have a role in prostate cancer growth and survival.