FERMA549061
Macrophages (Mature) Monoclonal Antibody (25F9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549061-Each-of-1 | In Stock | ₹ 45,879.50 |
FERMA549061 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,879.50
GST (18%): ₹ 8,258.31
Total Price: ₹ 54,137.81
Antigen
Macrophages (Mature)
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
25F9
Conjugate
Unconjugated
Gene Alias
Macrophages; Mature Macrophages
Immunogen
The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages.
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
4° C
Isotype
IgG1
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Description
- The antibody is associated with fully differentiated tissue macrophages both in normal and in diseased tissues, independently of the presence or absence of inflammation
- The antigen is absent on freshly isolated monocytes and other blood cells
- After 6 to 7 days culture human monocytes become positive
- Some melanoma and carcinoma cell lines are also positive
- Furthermore the monoclonal antibody 25F9 cross reacts with a subpopulation of macrophages of rhesus monkey, pig alveolar macrophages and Kupffer cells
- Macrophages are a type of white blood cell that plays a crucial role in the immune system
- They are responsible for detecting, engulfing, and destroying foreign substances, such as bacteria and viruses, as well as dead cells and debris
- Mature macrophages are found in various tissues throughout the body and are highly specialized to perform specific functions depending on their location
- For example, alveolar macrophages are found in the lungs and are responsible for removing foreign particles that are inhaled, while Kupffer cells are found in the liver and are responsible for removing old or damaged red blood cells
- Understanding the function and behavior of macrophages is crucial for developing new treatments for diseases such as cancer, autoimmune disorders, and infections.