FERMA549119

TLR9 Monoclonal Antibody (5G5), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549119-Each-of-1 In Stock ₹ 54,468.00

FERMA549119 - Each of 1

₹ 54,468.00

In Stock

Quantity

1

Base Price: ₹ 54,468.00

GST (18%): ₹ 9,804.24

Total Price: ₹ 64,272.24

Antigen

TLR9

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

Q9NR96

Gene Symbols

Tlr9

Immunogen

Purified fusion protein of extracellular domain of human TLR9 (AA 1-815) and human IgGFc

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

5G5

Conjugate

FITC

Gene

Tlr9

Gene Alias

CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

54106

Content And Storage

4° C, store in dark

Isotype

IgG2a

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Description

  • The monoclonal antibody 5G5 reacts with RAW macrophages and TLR9 transfected HEK293 cells, and is cross reactive with canine TLR9
  • The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity
  • TLRs are highly conserved from Drosophila to humans and share structural and functional similarities
  • They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
  • The various TLRs exhibit different patterns of expression
  • This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes
  • Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.