PR3 Monoclonal Antibody (PR3G-2), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549093-Each-of-1 | In Stock | ₹ 58,384.00 |
FERMA549093 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 58,384.00
GST (18%): ₹ 10,509.12
Total Price: ₹ 68,893.12
Antigen
PR3
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.
P24158
Gene Symbols
PRTN3
Immunogen
Monoclonal antibody PR3G-2 reacts with human proteinase 3 (PR3), a 30 kDa protein
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone
PR3G-2
Conjugate
FITC
Gene
PRTN3
Gene Alias
ACPA; AGP7; azurophil granule protein 7; CANCA; C-ANCA; C-ANCA antigen; leukocyte proteinase 3; MBN; MBT; mPR3; Myeloblastin; neutrophil proteinase 4; NP4; NP-4; P29; PR3; PR-3; Proteinase 3; PRTN3; serine proteinase, neutrophil; wegener autoantigen; Wegener granulomatosis autoantigen
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
5657
Content And Storage
4° C, store in dark
Isotype
IgG1
Related Products
Description
- The monoclonal antibody PR3G-2 was produced by immunization of mice with a crude granule extract
- Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246)
- By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369)
- May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279)
- [UniProt]