TNFR2 Monoclonal Antibody (80M2), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549127-Each-of-1 | In Stock | ₹ 67,773.50 |
FERMA549127 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 67,773.50
GST (18%): ₹ 12,199.23
Total Price: ₹ 79,972.73
Antigen
TNFR2
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.
P20333
Gene Symbols
Tnfrsf1b
Immunogen
The monoclonal antibody 80M2 recognizes the extracellular part of membrane-bound TNF-RII
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays
Clone
80M2
Conjugate
FITC
Gene
Tnfrsf1b
Gene Alias
CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
7133
Content And Storage
4° C, store in dark
Isotype
IgG1
Related Products
Description
- The monoclonal antibody 80M2 recognizes the extracellular part of- membrane-bound TNF-RII as well as- the soluble form of TNF-RII which is generated by proteolytic cleavage of the extracellular domain
- The antibody is a non-agonistic receptor modulating antibody
- It enhances in vitro TNF alpha responses by increasing the affinity of the soluble form of TNF-alpha for TNF-RII
- TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha
- It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha
- The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2
- TNFR2 mediates most of the metabolic effects of TNF-alpha.