FERMA549132

TNFR2 Monoclonal Antibody (MR2-1), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549132-Each-of-1 In Stock ₹ 67,773.50

FERMA549132 - Each of 1

₹ 67,773.50

In Stock

Quantity

1

Base Price: ₹ 67,773.50

GST (18%): ₹ 12,199.23

Total Price: ₹ 79,972.73

Antigen

TNFR2

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

P20333

Gene Symbols

Tnfrsf1b

Immunogen

sTNF-R75 purified from the culture supernatant of NSO cells (transfected with the extracellular part of TNF-R75)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Western Blot

Clone

MR2-1

Conjugate

FITC

Gene

Tnfrsf1b

Gene Alias

CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

7133

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • The antibody reacts with the extra-cellular part of the TNF-RII
  • It also reacts with the soluble receptor
  • The antibody cross reacts with rhesus and cynomolgus natural TNF-RII
  • TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha
  • It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha
  • The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2
  • TNFR2 mediates most of the metabolic effects of TNF-alpha.