MA1-950

Bcl-3 Monoclonal Antibody (Ham150-3.5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1-950-Each-of-1 In Stock ₹ 46,502.50

MA1-950 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

Bcl-3

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P20749, Q9Z2F6

Gene Symbols

Bcl3

Immunogen

Full length mouse Bcl-3 protein.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

ELISA, Flow Cytometry, Western Blot

Clone

Ham150-3.5

Conjugate

Unconjugated

Gene

Bcl3

Gene Alias

AI528691; B cell leukemia/lymphoma 3; B-cell CLL/lymphoma 3; B-cell leukemia/lymphoma 3; B-cell lymphoma 3 protein; B-cell lymphoma 3 protein homolog; B-cell lymphoma 3-encoded protein; BCL3; BCL-3; Bcl-3 protein; BCL4; chronic lymphatic leukemia protein; D19S37; Proto-oncogene BCL3

Host Species

Armenian Hamster

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

12051, 602

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-950 detects human and mouse Bcl-3 from transfected cells and shows no cross-reactivity to other Bcl isoforms
  • MA1-950 has been successfully used in Western blot and FACS procedures
  • By Western blot, this antibody detects an ∽47 kDa protein representing Bcl-3 from C57BI/6 human T cells and Bcl-3 transgenic ms T cells
  • MA1-950 immunogen is full length Bcl-3 protein from mouse
  • B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors
  • This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells
  • Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus
  • Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.