MA1082
Influenza A M2 Monoclonal Antibody (14C2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1082-Each-of-1 | In Stock | ₹ 47,926.50 |
MA1082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,926.50
GST (18%): ₹ 8,626.77
Total Price: ₹ 56,553.27
Antigen
Influenza A M2
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Virus
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
14C2
Conjugate
Unconjugated
Gene Alias
Influenza M2
Immunogen
M2 protein from A/WSN/33-infected CV1 cell lysate.
Quantity
100 μg
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-082 detects the N-terminal of the influenza A virus M2 protein
- MA1-082 has been successfully used in Western blot, Immunofluorescence, immunocytochemistry and immunoprecipitation procedures
- By Western blot, this antibody detects a ∽15 kDa protein representing the M2 protein
- MA1-082 has demonstrated the ability to immunoprecipitate M2 from [35s] cysteine-labeled WSN-infected cells
- MA1-082 has demonstrated the ability to restrict the replication of some strains of influenza A virus by binding to the extracellular N-Terminal domain
- The MA1-082 immunogen is M2 protein from A/WSN/33-infected CV1 cell lysate
- Influenza A virus is an enveloped virus encoding 10 polypeptides
- RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2)
- M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA
- M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain
- The M2 protein has been found to play a role in Influenza replication and assembly of virion particles
- Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication.