CHOP Monoclonal Antibody (9C8), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA1250-Each-of-1 | In Stock | ₹ 51,887.00 |
MA1250 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,887.00
GST (18%): ₹ 9,339.66
Total Price: ₹ 61,226.66
Antigen
CHOP
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P35638, P35639
Gene Symbols
DDIT3
Immunogen
A bacterially expressed, mouse CHOP fusion protein.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2b
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
9C8
Conjugate
Unconjugated
Gene
DDIT3
Gene Alias
C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; Ddit3; DDIT-3; ddit3.L; DNA damage inducible transcript 3; DNA damage inducible transcript 3 L homeolog; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; GADD153; growth arrest and DNA damage-inducible; growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154; transcription factor GADD153; Xchop; XELAEV_18013440mg
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
13198, 1649
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA1-250 detects CHOP protein in human and mouse samples
- MA1-250 has successfully been used in Western blot, immunoprecipitation, immunocytochemistry, and immunofluorescence procedures
- By Western blot, this antibody detects an ∽31 kDa protein representing CHOP from primary human fibroblast extract
- The MA1-250 immunizing protein corresponds to a bacterially expressed, mouse CHOP fusion protein
- Clone 9C8 has been shown to recognize an epitope in the N-terminal region of CHOP
- This antibody was orginally validated as part of a Thermo Scientific Cellomics High Content Screening Kit
- The antibody sold separately may have slightly different performance and may need to be further optimized for the best results
- GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta
- Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites
- Inversely, the C/EBP GADD153 dimer gains binding activity to other non classical C/EBP stress related targets
- Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress
- Examples of GADD153 inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.