Calprotectin Monoclonal Antibody (MAC387), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA133972-Each-of-1 | In Stock | ₹ 56,337.00 |
MA133972 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,337.00
GST (18%): ₹ 10,140.66
Total Price: ₹ 66,477.66
Antigen
Calprotectin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P05109, P06702, P27005, P28782, P28783, P31725, P50115, P50116, P50117
Gene Symbols
S100A8, S100A9
Immunogen
Human monocytes
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Baboon, Bovine, Canine, Equine, Feline, Goat, Guinea Pig, Human, Mouse, Non-human Primate, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone
MAC387
Conjugate
Unconjugated
Gene
S100A9
Gene Alias
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100008704, 100008985, 100061730, 100061766, 100735238, 100735514, 101084164, 101084419, 102168876, 102182273, 116547, 20201, 20202, 490461, 490463, 532569, 616818, 6279, 6280, 94195
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- For staining of paraffin sections, protein digestion pre-treatment (e.g
- trypsin), 0.1% for 10 minutes or antigen retrieval using heat treatment is required
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- The S100A8/A9 heterocomplex, also called MRP-8/MRP-14 complex or calprotectin, comprises 60% of the cytoplasmic protein fraction of circulating polymorphonuclear granulocytes and is also found in monocytes, macrophages and ileal tissue eosinophils
- Peripheral blood monocytes carry the antigen extra- and intracellularly, neutrophils only intracellularly
- The S100A8/A9 complex has antibacterial, antifungal, immunomodulating and antiproliferative effects
- Besides this it is a potent chemotactic factor for neutrophils
- Plasma concentrations are elevated in diseases associated with increased neutrophil activity, like inflammatory bowel disease
- Granulocytes terminate their existence after transmigration through the intestinal wall
- Therefore calprotectin is also detectable in feces
- Elevated levels of calprotectin have been observed in body fluids such as plasma, saliva, gingival crevicular fluid, stools, and synovial fluid during infection and inflammatory conditions.