MA171504

HIV1 nef Monoclonal Antibody (3A2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA171504-Each-of-1 In Stock ₹ 48,015.50

MA171504 - Each of 1

₹ 48,015.50

In Stock

Quantity

1

Base Price: ₹ 48,015.50

GST (18%): ₹ 8,642.79

Total Price: ₹ 56,658.29

Antigen

HIV1 nef

Classification

Monoclonal

Concentration

0.7 mg/mL

Formulation

PBS with 0.1% sodium azide; pH 7.4

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Target Species

Virus

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

3A2

Conjugate

Unconjugated

Gene Alias

HIV-1 Nef

Immunogen

Recombinant Nef protein of HIV-1 BRU purified from E. coli

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • This antibody reacts with HIV-1 Nef subtypes A, B, C
  • It recognizes BRU, IIIB, LAV and BH10 strains, and has been mapped to amino acids: 171-190 (HGMDDPEREVLEWRFDSRLA)
  • This clone may also be referred to as 3A2 (01-006)
  • HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells
  • The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus
  • The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells
  • It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD 4 and MH4, important for AIDS virus infection.