MA180360

CD31 Monoclonal Antibody (CO.3E1D4), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA180360-Each-of-1 In Stock ₹ 66,972.50

MA180360 - Each of 1

₹ 66,972.50

In Stock

Quantity

1

Base Price: ₹ 66,972.50

GST (18%): ₹ 12,055.05

Total Price: ₹ 79,027.55

Antigen

CD31

Classification

Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 1% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.

P51866

Gene Symbols

Pecam1

Immunogen

Ovine leucocytes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Goat, Ovine

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry

Clone

CO.3E1D4

Conjugate

FITC

Gene

Pecam1

Gene Alias

C85791; CD31; CD31 antigen; CD31, PECAM-1; CD31/EndoCAM; endoCAM; GPIIA'; I79_008304; PECA1; Pecam; PECAM1; Pecam-1; platelet and endothelial cell adhesion molecule 1; platelet endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule-1; platelet/endothelial cell adhesion molecule (CD31 antigen); platelet/endothelial cell adhesion molecule 1; type I transmembrane endothelial adhesion molecule

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100303608, 102179808, 282303

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form

Liquid

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Description

  • For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL
  • Mouse anti Sheep CD31 antibody, clone CO.3E1D4 recognizes ovine CD31, also known as PECAM-1.Ovine CD31 is predominantly expressed by peripheral blood platelets and a small percentage of lymphocytes
  • CD31 (platelet endothelial cell adhesion molecule-1, PECAM-1) is an inhibitory coreceptor involved in regulation of T cell and B cell signaling by a dual immunoreceptor tyrosine-based inhibitory motif (ITIM) that upon associated kinases-mediated phosphorylation provide docking sites for protein-tyrosine phosphatases
  • CD31 is expressed ubiquitously within the vascular compartment and is located mainly at junctions between adjacent cells
  • N-terminal Ig-like domain of CD31 is responsible for its homophilic binding, which plays an important role in cell-cell interactions
  • CD31 is a multifunctional molecule with diverse roles in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, negative regulation of immunoreceptor signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis
  • It is one of key regulatory molecules in vascular system.