E-selectin Monoclonal Antibody (UZ7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA106507-Each-of-1 | In Stock | ₹ 53,311.00 |
MA106507 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,311.00
GST (18%): ₹ 9,595.98
Total Price: ₹ 62,906.98
Antigen
E-selectin
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P16581, Q00690
Gene Symbols
SELE
Immunogen
LPS-activated mLEND1 cells expressing E-selectin at their cell surface.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG2a
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot, Western Blot
Clone
UZ7
Conjugate
Unconjugated
Gene
SELE
Gene Alias
CD62 antigen-like family member E; CD62E; e selectin; Elam; ELAM1; ELAM-1; endothelial adhesion molecule 1; endothelial leukocyte adhesion molecule; endothelial leukocyte adhesion molecule 1; endothelial leukocyte adhesion molecule I; ESEL; E-selectin; LECAM2; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; RP1-117P20.2; SELE; selectin E; selectin E (endothelial adhesion molecule 1); selectin, endothelial cell
Host Species
Rat
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
20339, 6401
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- MA1-06507 detects E-selectin in mouse samples
- MA1-06507 has sucessfully been used in flow cytometry, immunocytochemistry, immunofluorescence, Western blotting, immunoprecipitation, immunohistochemistry and ELISA
- The MA1-06507 immunogen is LPS-activated mLEND1 cells expressing E-selectin at their cell surface
- Leukocytes adhere to the blood vessel endothelium during extravasation in postcapillary venules of lymph nodes
- In addition, leukocyte adhesion occurs in the capillaries and small venules at any site in the body after onset of inflammation
- This response is immediate and involves a cascade of adhesion receptors
- At the endothelial surface members of the selectin and immunoglobulin superfamilies participate in this cascade
- Selectins are C-type cell surface lectins that play a role in leukocyte adhesion to the blood vessel wall endothelium
- E-selectin (CD62E) is an endothelial cell specific selectin that is expressed only after activation with proinflammatory cytokines
- In vitro experiments have shown that IL-1, TNFalpha and bacterial wall components like lipopolysaccharides induce the transcription of E-selectin in a NFkB dependent signaling cascade
- E-selectin has been associated with blood vessel endothelium in diverse inflammatory situations.