MA190668

ICAM-1 Monoclonal Antibody (P1W16), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA190668-Each-of-1 In Stock ₹ 50,062.50

MA190668 - Each of 1

₹ 50,062.50

In Stock

Quantity

1

Base Price: ₹ 50,062.50

GST (18%): ₹ 9,011.25

Total Price: ₹ 59,073.75

Antigen

ICAM-1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P05362

Gene Symbols

ICAM1

Immunogen

Cell preparation: V(+)B2- Human Ocular melanoma line.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

P1W16

Conjugate

Unconjugated

Gene

ICAM1

Gene Alias

BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells

Host Species

Mouse

Purification Method

IgG fraction

Regulatory Status

RUO

Gene ID (Entrez)

3383

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recommended positive controls: Positive control lysate: A375M melanoma cell line or tonsil 85-115 kDa MW
  • ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain
  • ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102)
  • ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor
  • ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation
  • ICAM-1 is also detected in some carcinoma and melanoma cells
  • Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.