Endothelin 1 Monoclonal Antibody (TR.ET.48.5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3005-Each-of-1 | In Stock | ₹ 48,282.50 |
MA3005 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,282.50
GST (18%): ₹ 8,690.85
Total Price: ₹ 56,973.35
Antigen
Endothelin 1
Classification
Monoclonal
Concentration
2.5 mg/mL
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P05305, P22387, P22388, Q9BG76
Gene Symbols
EDN1
Immunogen
Pure endothelin-1 conjugated to KLH.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Ovine, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Radioimmune Assays (RIA), Western Blot
Clone
TR.ET.48.5
Conjugate
Unconjugated
Gene
EDN1
Gene Alias
ARCND3; Big endothelin 1; Big endothelin-1; Big ET; Big ET 1; Big ET1; BigET; EDN1; endothelin 1; endothelin-1; Et; ET1; ET-1; HDLCQ7; PPET1; ppET-1; preproendothelin; preproendothelin-1; preproET; QME
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
13614, 1906, 24323, 443498
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- MA3-005 detects ET-1 from human, sheep, mouse and rat tissues
- This antibody shows little cross-reactivity to related peptides and no known cross-reactivity to non-related peptides
- MA3-005 has been successfully used in Western blot, flow cytometry, immunofluorescence, immunohistochemistry, immunocytochemistry, and radioimmune assay procedures
- Immunohistochemical staining of ET-1 in human corpus cavernosum tissue with MA3-005 results in staining of endothelial cells
- Radioimmune assays using MA3-005 can be used to concentrate ET-1 in solution (e.g
- serμm/plasma, milk, urine)
- This antibody is not recommended for human placenta tissue or HepG2 cells in Western blot applications
- For immunohistochemistry with MA3-005 formalin-fixed, paraffin-embedded tissue sections has been used
- The MA3-005 antigen is purified human endothelin-1
- Studies suggest that this antibody binds to an epitope in the region of ET-1 represented by amino acids 8-16
- The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1
- This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells
- Endothelin 1 also can affect the central nervous system
- Two transcript variants encoding different isoforms have been found for this gene.