MA3012

HSP60 Monoclonal Antibody (4B9/89), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3012-Each-of-1 In Stock ₹ 56,337.00

MA3012 - Each of 1

₹ 56,337.00

In Stock

Quantity

1

Base Price: ₹ 56,337.00

GST (18%): ₹ 10,140.66

Total Price: ₹ 66,477.66

Antigen

HSP60

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

antibody with no preservative

Gene Accession No.

P10809, P63038, P63039

Gene Symbols

HSPD1

Immunogen

Human placental HSP60.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

4B9/89

Conjugate

Unconjugated

Gene

HSPD1

Gene Alias

60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; 60kDa; Chaperonin 60; CPN60; GROEL; heat shock 60kD protein 1 (chaperonin); heat shock 60kDa protein 1; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; heat shock protein 1 (chaperonin); heat shock protein 60; heat shock protein 60 (liver); heat shock protein 65; heat shock protein family D (Hsp60) member 1; heat shock protein, 60 kDa; HLD4; HSP; Hsp60; HSP-60; Hsp60s1; HSP65; HSP-65; Hspd1; Hspd1-30p; HuCHA60; hypothetical protein; I79_011398; mitochondrial matrix protein P1; P1 protein; P60 lymphocyte protein; RCJMB04_7g5; short heat shock protein 60 Hsp60s1; SPG13; Unknown (protein for IMAGE:7943409)

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

15510, 3329, 63868

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Lyophilized

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Description

  • MA3-012 detects heat shock protein 60 kDa (HSP60) from human, mouse, rat, and primate cells, tissues and recombinant protein preparations
  • MA3-012 has been successfully used in Western blot, flow cytometry, immunocytochemistry and ELISA procedures
  • By Western blot, this antibody detects a single 58 kDa protein representing HSP60 from human blood samples
  • Immunocytochemical staining of HSP60 in B-SC-1 cells with MA3-012 yields a pattern consistent with the mitochondrial localization of HSP60
  • The MA3-012 antigen is human placental HSP60
  • Epitope mapping studies using human HSP60 deletion mutants suggest that this antibody binds either between amino acids 335-366 or 484-547
  • Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
  • This replacement antibody is now recommended for researchers who need an antibody for high content cell based assays
  • It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
  • Further optimization including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody may have to be performed for your high content assay
  • Reconstitute in 100 μL PBS to create a stock of 1 mg/mL
  • This gene encodes a member of the chaperonin family
  • The encoded mitochondrial protein may function as a signaling molecule in the innate immune system
  • This protein is essential for the folding and assembly of newly imported proteins in the mitochondria
  • This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter
  • Several pseudogenes have been associated with this gene
  • Two transcript variants encoding the same protein have been identified for this gene
  • Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.