MA3044

CHRM2 Monoclonal Antibody (31-1D1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3044-Each-of-1 In Stock ₹ 46,146.50

MA3044 - Each of 1

₹ 46,146.50

In Stock

Quantity

1

Base Price: ₹ 46,146.50

GST (18%): ₹ 8,306.37

Total Price: ₹ 54,452.87

Antigen

CHRM2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

antibody with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P06199, P08172, P10980, Q9ERZ4

Gene Symbols

CHRM2

Immunogen

Purified porcine cardiac m2 muscarinic acetylcholine receptor.

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

31-1D1

Conjugate

Unconjugated

Gene

CHRM2

Gene Alias

7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1129, 243764, 397498, 81645

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA3-044 detects muscarinic 2 acetylcholine receptor (m2AChR) from human, mouse, pig and rat tissues
  • This antibody does not detect mAChR from chicken tissues
  • MA3-044 is specific for the m2 mAChR subtype
  • MA3-044 has been successfully used in Western blot and immunoprecipitation protocols
  • MA3-044 is an ∽52kDa protein; however, by Western blot this antibody may detect 60-80 kDa protein(s) (depending on the degree of glycosylation) representing the m2AChR from pig heart
  • The MA3-044 antigen is purified porcine cardiac m2 AChR
  • Muscarinic cholinergic receptor 2 (CHRM2) is an Acetylcholine Receptor has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release
  • The M2 receptor has also been suggested to mediate smooth muscle contractility
  • Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain
  • Increase in M2 receptor heterozygosity has been associated with depression in women
  • The M2 receptor has been reported to be expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, and in lung and prostate.