SERCA1 ATPase Monoclonal Antibody (IIH11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3911-Each-of-1 | In Stock | ₹ 47,303.50 |
MA3911 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,303.50
GST (18%): ₹ 8,514.63
Total Price: ₹ 55,818.13
Antigen
SERCA1 ATPase
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites diluted in PBS with 0.05% sodium azide
Gene Accession No.
O14983, P04191, Q64578, Q8R429
Gene Symbols
ATP2A1
Immunogen
Purified rabbit skeletal muscle sarcoplasmic reticulum.
Regulatory Status
RUO
Gene ID (Entrez)
100037716, 100726234, 116601, 11937, 479797, 487
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Clone
IIH11
Conjugate
Unconjugated
Gene
ATP2A1
Gene Alias
adult Ca2+ ATPase; ATP2A; ATP2A1; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; ATPase, Ca++ transporting, ubiquitous; Ca2+ ATPase; calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; neonatal Ca2+ ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA; SERCA ATPase; Serca1; SERCA1a; SR Ca(2+)-ATPase 1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Canine, Guinea Pig, Human, Mouse, Rabbit, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-911 detects sarcoplasmic or endoplasmic reticulum calcium 1 (SERCA1) ATPase from canine, human, rabbit, rat, mouse and guinea pig tissues
- MA3-911 has been successfully used in Western blot, immunohistochemistry, and immunofluorescence procedures
- By Western blot, this antibody detects an ∽110 kDa protein representing SERCA1 ATPase in canine skeletal muscle extracts
- Immunofluorescence staining of SERCA1 ATPase in canine skeletal muscle with MA3-911 results in strong labeling of the entire type II (fast) myofiber
- The MA3-911 antigen is purified rabbit skeletal muscle sarcoplasmic reticulum
- This antibody recognizes an epitope between amino acids 199-505 of rabbit skeletal muscle ATPase, a region that is not exposed in native sarcoplasmic reticulum
- ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations
- The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases
- The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle
- The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types
- The SERCA3 gene is not as well characterized and is found in non-muscle cells.