NFATC1 Monoclonal Antibody (7A6), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3024-Each-of-1 | In Stock | ₹ 49,261.50 |
MA3024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,261.50
GST (18%): ₹ 8,867.07
Total Price: ₹ 58,128.57
Antigen
NFATC1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites diluted in PBS with 0.05% sodium azide
Gene Accession No.
O88942, O95644
Gene Symbols
NFATC1
Immunogen
Bacterially expressed glutathione S-transferase (GST) fusion protein containing NF-ATc1 residues 1-654.
Regulatory Status
RUO
Gene ID (Entrez)
100361818, 18018, 4772
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ChIP Assay, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone
7A6
Conjugate
Unconjugated
Gene
NFATC1
Gene Alias
2210017P03Rik; AI449492; AV076380; MGC138448; NFAT tra; NFAT trans; NFAT transcription complex cytosolic component; NFAT2; NFATc; NF-ATC; NFATC1; NF-ATc1; NF-ATc1.2; Nfatcb; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1; nuclear factor of activated T-cells 1; nuclear factor of activated T-cells 'c'; nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; transcription factor NF-ATc
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-024 detects NFATc1 (NFAT2) from transfected human, rat, mouse, and monkey cells
- This antibody does not cross react with NFATc2 (NFAT1)
- MA3-024 has been successfully used in Western blot, immunoprecipitation, ChIP, immunofluorescence and gel shift procedures
- By Western blot, this antibody detects an ∽105 kDa band representing transfected NFAT2 from COS cell lysate
- The MA3-024 immunogen is bacterially expressed glutathione S-transferase (GST) fusion protein containing NF-ATc1 residues 1-654
- Antibodies to this protein (and modification) were previously sold as part of a Thermo Scientific Cellomics High Content Screening Kit
- This replacement antibody is now recommended for researchers who need an antibody for high content cell-based assays
- It has been thoroughly tested and validated for cellular immunofluorescence (IF) applications
- Further optimization, including the selection of the most appropriate fluorescent Dylight conjugated secondary antibody, may have to be performed for your high content assay
- The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex
- This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component
- Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response
- The product of this gene is an inducible nuclear component
- It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A
- Five transcript variants encoding distinct isoforms have been identified for this gene
- Different isoforms of this protein may regulate inducible expression of different cytokine genes.