MS1105R1
Epredia™ Lab Vision™ TdT/Terminal Deoxyribonucleotidyl Transferase Ab-1 Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TdT/Terminal Deoxyribonucleotidyl Transferase Ab-1
Classification
Monoclonal
Conjugate
Unconjugated
Immunogen
Recombinant protein corresponding to the amino terminal region of the TdT molecule
Regulatory Status
IVD
Primary or Secondary
Primary
Content And Storage
Store at 4°C, Do Not Freeze
Isotype
IgG2a
Applications
Immunohistochemistry (Paraffin)
Clone
SEN28
Host Species
Mouse
Quantity
1 mL
Research Discipline
DNA Repair
Target Species
Human
Form
Prediluted
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Description
- Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyses the polymerization of deoxynucleotides at the 3' hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template
- TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leuksemias
- The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt's lymphoma
- Host Species: Mouse Clone: SEN28 Isotype: IgG2a Species Reactivity: Human
- Does not react with rat
- Others not known
- Epitope: N-terminal Immunogen: Recombinant protein corresponding to the amino terminal region of the TdT molecule Molecular Weight: 58kDa Positive Control: Thymus Cellular Localization: Nuclear Ab-1 will be of use in the differentiation of lymphoblastic lymphoma from other lymphomas
- Recommended for: Immunohistochemistry (Formalin/paraffin)