MUC5AC Antibody (45M1), PE/Cy7, Novus Biologicals™

MUC5AC

Monoclonal

PE-Cyanine7

PBS with 0.05% Sodium Azide

MUC5AC

M1 mucin preparation from the fluid of an ovarian mucinous cyst belonging to an O Le(a-b) patient

0.1 mL

Primary

This monoclonal antibody recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC).Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

45M1

Flow Cytometry

gastric mucin, leB, lewis B blood group antigen, major airway glycoprotein, MUC5, mucin 5, subtypes A and C, tracheobronchial/gastric, mucin 5AC, oligomeric mucus/gel-forming, mucin 5AC, oligomeric mucus/gel-forming pseudogene, mucin-5 subtype AC, tracheobronchial, mucin-5AC, TBM, tracheobronchial mucin

Mouse

Protein A or G purified

Cellular Markers, Extracellular Matrix, Infections (Virus Bacteria and Parasites), Signal Transduction

4586.0

Human, Mouse, Rat, Porcine, Chicken, Feline, Primate, Rabbit, Bovine (Negative)

IgG1 κ