MUC1 Antibody (GP1.4), PE/Cy5.5, Novus Biologicals™

MUC1

Monoclonal

PE-Cyanine5.5

PBS with 0.05% Sodium Azide

MUC1

Human milk fat globule membranes (Uniprot: P15941 )

0.1 mL

Primary

In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. This monoclonal antibody reacts with the DTRP epitope in the tandem repeats. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

GP1.4

Flow Cytometry

Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Mouse

Protein A or G purified

Cancer, Cellular Markers, Extracellular Matrix, Inflammation, Signal Transduction

4582.0

Human

IgG1 κ