TAG-72 Antibody (B72.3 + CC49), PE/Atto594, Novus Biologicals™

TAG-72

Monoclonal

PE/ATTO 594

PBS with 0.05% Sodium Azide

Mouse

Protein A or G purified

Primary

Human, Rat, Bovine, Canine

IgG1 κ

Flow Cytometry

B72.3 + CC49

Flow Cytometry

CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72

Membrane-enriched fraction of a human breast carcinoma liver metastasis (B72.3); Purified TAG-72 protein (CC49)

0.1 mL

Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This monoclonal antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Store at 4°C in the dark. Do not freeze.