StAR Antibody (STAR/2140), Alexa Fluor™ 488, Novus Biologicals™

StAR

Monoclonal

Alexa Fluor 488

50mM Sodium Borate with 0.05% Sodium Azide

STAR

Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)

0.1 mL

Cancer

Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Store at 4°C in the dark.

Immunohistochemistry, Immunohistochemistry (Paraffin)

STAR/2140

Immunohistochemistry, Immunohistochemistry-Paraffin

cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial

Mouse

Protein A or G purified

RUO

Primary

Human

IgG2b κ