CEACAM5/CD66e Antibody (SPM330), Allophycocyanin/Cy7, Novus Biologicals™

CEACAM5/CD66e

Monoclonal

APC-Cyanine7

PBS with 0.05% Sodium Azide

CEACAM5

Purified human CEACAM5/CD66e protein (Uniprot: P06731)

0.1 mL

Primary

This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This monoclonal antibody reacts with nonspecific cross-reacting antigen (NCA) and shows a cross-reaction with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbladder, urachus, salivary gland, ovary, and endocervix.

Store at 4°C in the dark. Do not freeze.

Flow Cytometry

SPM330

Flow Cytometry

Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100

Mouse

Protein A or G purified

Apoptosis, Cancer, Cellular Markers, Immunology

1048.0

Human, Monkey

IgG1 κ