TIMP-3 Antibody, Novus Biologicals™

TIMP-3

Polyclonal

Unconjugated

PBS with 0.05% BSA. with 0.05% Sodium Azide

HSMRK222, K222, K222TA2, metalloproteinase inhibitor 3, MIG-5 protein, Protein MIG-5, pseudoinflammatory), SFD, TIMP metallopeptidase inhibitor 3, TIMP-3, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, Tissue inhibitor of metalloproteinases 3

Rabbit

30 kDa

0.1 mg

Angiogenesis, Apoptosis, Cancer, Hypoxia, Metastasis, Vision

7078

Human, Bovine, Canine, Equine, Sheep

Purified

Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

0.2 mg/ml

Flow Cytometry 0.5-1ug/million cells, Immunohistochemistry 1-2ug/ml, Immunocytochemistry/Immunofluorescence 1-2ug/mlimmunohistochemistry 1-2ug/ml, Immunohistochemistry-Paraffin

P35625

TIMP3

TIMP-3 (aa175-211) (Uniprot: P35625)

Protein A purified

RUO

Primary

TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Store at 4C.

IgG