CD27 Ligand/TNFSF7/CD70 Antibody (BU69), Novus Biologicals™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP24454500-Each-of-1 | In Stock | ₹ 23,852.00 |
NBP24454500 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 23,852.00
GST (18%): ₹ 4,293.36
Total Price: ₹ 28,145.36
Antigen
CD27 Ligand/TNFSF7/CD70
Classification
Monoclonal
Concentration
0.2 mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunoprecipitation 0.5 - 1 ug/500ug Protein Lysate, Immunohistochemistry-Frozen 0.5 - 1 ug/ml, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Alias
CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7
Host Species
Mouse
Molecular Weight of Antigen
30 kDa
Quantity
0.02 mg
Research Discipline
Apoptosis
Gene ID (Entrez)
970
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunoprecipitation, Immunohistochemistry (Frozen), Immunofluorescence
Clone
BU69
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
CD70
Immunogen
Human WM-1 (Waldenstrom s macroglobulinemia) cell line
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Ensure accurate, reproducible results in ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Immunofluorescence CD27 Ligand/TNFSF7/CD70 Monoclonal specifically detects CD27 Ligand/TNFSF7/CD70 in Human samples
- It is validated for Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, Immunofluorescence.