NBP24514900

EGFR Antibody (SPM622), Novus Biologicals™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP24514900-Each-of-1 In Stock ₹ 24,920.00

NBP24514900 - Each of 1

₹ 24,920.00

In Stock

Quantity

1

Base Price: ₹ 24,920.00

GST (18%): ₹ 4,485.60

Total Price: ₹ 29,405.60

Antigen

EGFR

Classification

Monoclonal

Concentration

0.2mg/mL

Dilution

Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml

Gene Accession No.

P00533

Gene Symbols

EGFR

Immunogen

Human EGFR purified from A431 cells

Quantity

0.02 mg

Research Discipline

Cancer, Cell Biology, Cell Cycle and Replication, Growth and Development, Hypoxia, Signal Transduction, Tumor Suppressors, Tyrosine Kinases

Gene ID (Entrez)

1956

Target Species

Human

Form

Purified

Applications

Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Clone

SPM622

Conjugate

Unconjugated

Formulation

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

Gene Alias

avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage

Store at 4C.

Isotype

IgG1 κ

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Description

  • Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence EGFR Monoclonal specifically detects EGFR in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence.