NBP247674B

CD4 Antibody (C4/206) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Fischer Scientific

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Antigen

CD4

Classification

Monoclonal

Concentration

1.0 mg/mL

Dilution

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

Gene Alias

CD4 antigen, CD4 antigen (p55), CD4 molecule, CD4 receptor, CD4mut, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Immunogen

Recombinant human CD4 protein

Purification Method

Protein A or G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Recognizes a protein of 55kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified

Content And Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunofluorescence, CyTOF

Clone

C4/206

Conjugate

Unconjugated

Formulation

PBS with No Preservative

Host Species

Mouse

Molecular Weight of Antigen

55 kDa

Quantity

0.2 mg

Research Discipline

Adaptive Immunity, Cell Biology, Cellular Markers, Cytokine Research, Immunology, Innate Immunity, Regulatory Immunology, Stem Cell Markers

Gene ID (Entrez)

920

Target Species

Human

Form

Purified

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Description

  • CD4 Monoclonal specifically detects CD4 in Human samples
  • It is validated for ELISA.