CD2 Antibody (HuLy-m1) - Azide and BSA Free, Novus Biologicals™

CD2

Monoclonal

1.0 mg/mL

Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready

CD2 antigen, CD2 antigen (p50), sheep red blood cell receptor, CD2 molecule, Erythrocyte receptor, FLJ46032, LFA-2, LFA-3 receptor, lymphocyte-function antigen-2, Rosette receptor, SRBC, T11, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5

Mouse

50 kDa

0.2 mg

Adaptive Immunity, Apoptosis, Immunology

914

Human, Feline

Purified

Flow Cytometry, Immunofluorescence, CyTOF

HuLy-m1

Unconjugated

PBS with No Preservative

CD2

Human thymocytes

Protein A or G purified

RUO

Primary

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

IgG2b κ