Arginase 1/ARG1/liver Arginase Antibody (ARG1/1125) - IHC-Prediluted, Novus Biologicals™

Arginase 1/ARG1/liver Arginase

Monoclonal

Unconjugated

10mM PBS and 0.05% BSA with 0.05% Sodium Azide

ARG1

Recombinant human Arginase 1/ARG1/liver Arginase protein fragment (around aa11-97) (exact sequence is proprietary) (Uniprot: P05089)

Protein A or G purified

RUO

Primary

Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.

Store at 4C.

IgG3 κ

Immunohistochemistry (Paraffin)

ARG1/1125

Immunohistochemistry-Paraffin

arginase 1, arginase, liver, arginase-1, EC 3.5.3.1, Liver-type arginase, Type I arginase

Mouse

36.5 kDa

7 mL

Cancer, Cellular Markers, Chromatin Research, Lipid and Metabolism, Myeloid derived Suppressor Cell

383

Human

Purified